Reprofit

Common causes for egg donation treatment

Premature menopause (premature failure of the ovarian fonction).
Genetic causes.
Very poor quality of the eggs.
Conditions following cancer treatment (chemotherapy and radiotherapy).
Conditions following ovarian surgery.
Severe endometriosis.

We perform the highest number of cycles in the Czech Republic

The REPROFIT clinic has specialized in treatment with donated eggs since its foundation. Thanks to many years of experience, we have one of Europe's most sophisticated donor programmes. Every year we provide care to clients from all over the world. We have an extensive database of donors and can provide treatment without waiting.

Information about the egg donation treatment

The DIVF process starts with hormonal stimulation of the female donor, which is necessary to obtain a larger quantity of eggs than in the periodical ovulation cycle. The partner’s sperm is taken on the day the female donor’s eggs are taken. The eggs obtained are subsequently fertilized by the sperm and the embryos created are further preserved (cultivated) outside the woman’s body. After several days of cultivation, the best embryo is transferred to the female donee’s uterus - Embryotransfer. The remaining quality embryos can be frozen and preserved for further treatment.

Contact us

By phone or online

First visit/online consultation, donor selection

Stimulation protocol, cycle synchronization

4 - 6 weeks

Oocyte retrieval

Fertilization

5 – 6 days

Embryo transfer

Normal daily routine

12 days

Positive pregnancy test

Contact us through our

Online form

Treatment Success Rate

In the first DIVF cycle, 60 - 70 % of women achieve pregnancy.

Guarantee of Egg Donation Treatment

We guarantee 2 high-quality embryos. The number of embryos for transfer is decided by the physician following consultation with the couple.
The examination and selection of donors take place under the strict criteria laid down by the European Society of Human Reproduction and Embryology (ESHRE).
We use our extensive database to select a suitable donor matching the patient's specifications (height, weight, the colour of eyes and hair).

If there is an error on the donor’s part (does not take her medication, falls ill, terminates stimulation), we will find a substitute donor meeting your requirements as soon as possible to carry out the treatment without interruption.
Unless the donor’s eggs (fresh or frozen) can be fertilized using ICSI, we will offer you free treatment. This offer applies only if the sperm is of good quality. If fertilization fails dues to the poor quality of sperm, we regret that there is no other free cycle to offer.

If only one quality embryo is available, you will receive a 40% discount.
We regret that the cost of medication spent for the treatment cycle without transfer cannot be refunded.
If you ask to cancel the treatment before retrieval of the donor egg, we will refund you the aliquot part of the deposit.

We also recommend

Examination by your gynaecologist no older than 6 months – Ultrasound examination, STD tests (sexually transmitted diseases).
Mammograph screening in women over 45 years.

Donor egg collection

Oocytes are obtained from the donor by suction of follicles with a thin needle through the vagina wall under ultrasonic control. Like hormonal stimulation, oocyte puncture is undergone at our clinic by hundreds of donors every year.

Embryo quality assessment

The success of fertilization is checked by the embryologist under the microscope 16 - 18 hours after fertilization. The embryos formed are called pronuclei. Their number depends on the quality of sperm, eggs and fertilization method. It is very difficult to assess the quality of embryos at the pronucleus stage. Prolonged cultivation is used to assess the quality of embryos. The embryos grow to higher stages in special media.

Prolonged cultivation enables embryos that develop normally to be distinguished from those whose development is slowing down or ceased, and quality embryos for transfer to be selected. The decision about which day of cultivation is most suitable for embryo transfer depends on the quantity and development stages of each embryo, and is fully in the hands of the embryologist.

What is assisted hatching?

A special laboratory method that consists in disrupting the protective layer of the embryo, the so-called zona pellucida. It is mainly used for embryos before the planned preimplantation genetic testing (PGT) or in exceptional cases on the recommendation of an embryologist. For example, if the zona pellucida is too thick or hard. In other cases it is unnecessary to perform this method. A viable embryo can cope with leaving the zona pellucida and subsequent nidation on its own.

On which day is the embryo transfer performed?

The transfer of embryos to the uterus is usually carried out on day 5-6 after egg retrieval. The decision of which day of culture is the most suitable for embryo transfer depends on the number and developmental stages of individual embryos.

How does embryo transfer work?

The transfer is painless and is performed without general anaesthesia. It is similar to a normal gynaecological examination. The doctor introduces the embryo into the uterus under the direct observation of ultrasound. The patient and her partner can see their embryo on a monitor and then watch its transfer into the uterus.

Return to normal everyday life after the transfer

After the transfer, the woman remains lying peacefully on the ward for 10 - 15 minutes, after which the nurse prepares the required prescriptions and accompanies her to the economic department for the conclusion of treatment.

On the day of transfer and the following two days, rest is recommended. From the third day after the transfer it is possible to return to normal daily life.

Family Completion Program

Repeat donation

After so many years of experience with donor egg treatment, we often meet patients who wish to have further treatment using eggs from the same donor who helped them conceive a child.

Two or more years after treatment, when patients are considering further treatment, more than 50% of donors are not interested in donating again. For this reason, we have introduced the option of preserving eggs from the same donor or sperm from a selected donor for possible further treatment.

Preservation of donor eggs for possible further treatment

Our unique family completion program brings about the opportunity for family planning and preservation of eggs of a selected donor for possible future treatment.

Preservation of donor's sperm for possible second cycle

As in the case of donated eggs, we also offer an opportunity for family planning and use of a selected donor sperm for possible further treatment. If any further treatment in the future is required, please consult it in advance. Donated sperm is rare biological material and sperm from the same donor can't always be guaranteed.

Who are our donors and how we examine them

Voluntary donors are young women under 32 years of age. Our clinic uses only eggs from young healthy donors and never uses surplus eggs from our patients. To enter the donation programme the donor must meet very strict criteria defined by the European directives.

Most of our donors are students or mothers on maternity leave. None of them are treated at our clinic with infertility issues, and oocyte donation is their voluntary decision. According to Czech law, oocyte donation is completely anonymous. It is strictly forbidden to facilitate any meetings between the donor and the recipient.

Before the actual inclusion in the donation program...

At the time of donation, all donors are tested in compliance with European tissue legislation and the recommendations of professional associations (ESHRE, Czech Society of Medical Genetics and Genomics SLG ČLS JEP). Besides gynaecological and ultrasound examinations, the donor must also pass sexually transmitted disease tests (HIV, hepatitis B, hepatitis C and syphilis) and a drug test.

The donors also undergo a consultation with a clinical geneticist and a genetic examination under the currently valid recommendations of the Czech Society of Medical Genetics and Genomics SLG ČLS JEP. We have started to use a carrier test for the genetic examination. Thanks to this test, we can reduce the risk of transmission of genetic diseases to the child. We use the carrier test with all newly registered donors to exclude serious genetic mutations, e.g. cystic fibrosis, spinal muscular atrophy, deafness and others. The carrier test also allows us to use the extensive possibilities of this screening when examining the genetic burden of a particular infertile couple. Additionally, we can continuously expand the spectrum of genetic examinations of donors as knowledge advances within the field.

The selection of donor women by the doctor takes place well in advance

The aim is to achieve the best possible match with the requirements of the recipient (patient). The vast majority of our donors are citizens of the Czech Republic. Thanks to our extensive database of donors, we can select one that matches the genetic and physical characteristics of the patient. Donor selection is based on your requirements and specifications. When selecting a donor, we try to ensure that the blood type of the donor matches the blood type of one of the couple. However, a different blood type does not affect the success of the treatment. When selecting a donor, we take into account other characteristics such as weight, height, hair and eye colour and educational attainment.

Because Reprofit is the most sought after egg donation clinic in the country, we have the ability to select your ideal donor without waiting.

Will I get detailed information about the egg donor?

The anonymity of donors of reproduction cells is required by Czech legislation (Act No. 373/2011 Coll., on specific health services). Since 2010, only information about the donor's year of birth, blood group, hair colour, eye colour, height and weight has been provided to protect donors. Other information about donors and donor women will not be provided to patients.

Procedure for searching for egg donors

Since 2006, our clinic has had a dedicated team focusing on the donation program.
The selection of egg donors is governed by Law 296/2008 Coll. and Decree 422/2008 Coll. and Law 373/2011 Coll. These laws represent the common European Tissue Directive (European Tissue Dirrectives 2004/23/EC), whose compliance is controlled in the Czech Republic by the State Institute for Drug Control (SÚKL).

More than 1,500 women a year come forward to donate. However, during the selection process, approximately 40% of women interested in donation are excluded.

The several step process for selecting the right donor:

Initial information interview and filling of questionnaires (medical condition, education, interests, family medical history).
Drug test.
Blood sampling to test for infections, genetics and indicators of ovarian reserve.
Genetic consultation.
Consultation with our physician and gynaecological examination.
Evaluation of test results and assessment of aptitude for donation.
Plan of the term for donation and explanation of stimulation, synchronisation and matching (of suitable donor with the recipient).
Stimulation process and egg retrieval.

2-3 months from initial interview to donation

List of performed genetic tests

Further tests if required by the recipients, are not included in the price of treatment and must be paid separately (e.g., Tay-Sachs, FRAX and other tests).