Other laboratory methods
We provide all available methods of assisted reproduction that can shorten your path to a successful pregnancy.
Assisted hatching is a special laboratory method that consists in breaking the protective layer of the embryo, the so-called zone pellucida. It is mainly used for embryos before planned pre-implantation genetic testing (PGT) or on the recommendation of an embryologist. For example, if the zona pellucida is too thick or hard. In most cases, the viable embryo will manage to leave the zona pellucida and subsequent nidation on its own.
Extended culture of embryos usually takes 5 to 6 days and yields significantly better results compared to culture for 2 to 3 days.
Up to 30-50% of embryos that develop correctly from the beginning will later stop developing. Already in the first 5 days of cultivation, it is clear for some of the embryos that they have no chance of further development, the cells no longer divide. So after 5 days, we get embryos with a high chance of implanting in the uterus, which saves our patients the disappointment of failed transfers.
During natural conception, the embryo reaches the uterus only in the so-called blastocyst phase, which also occurs after 5 days of development. Thanks to prolonged cultivation, we can let the embryos mature to the blastocyst stage, which simulates the natural development of pregnancy.
Another advantage is that from embryos that have undergone extended culture, we can collect cells for pre-implantation genetic testing, which allows us to screen for potential genetic anomalies.
EmbryoGlue is a transfer medium that contains a high concentration of hyaluronan and can increase the chance of embryo attachment in the endometrium after embryo transfer.
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